rs997509

A SNP in the ENPP1 gene on chromosome 6. Its most notable genotype is C;C: common in complete genomics

Gene
ENPP1
Location
Chr 6131,846,837 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
4%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.095% of people
  2. C;TNot ratedNo summary available.Typical · 0.05% of people

On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 95% C;T 5%
  • European ancestry (Utah)C;C 92% C;T 8%
  • Han Chinese (Beijing)C;C 100% C;T 0%
  • Japanese (Tokyo)C;C 100% C;T 0%
  • Yoruba (Nigeria)C;C 87% C;T 11%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs997509 increases the risk of Type-2 diabetes for the obese. *rs997509 we found a new SNP, rs997509, in intron 1 that is strongly associated with risk of type 2 diabetes in obese individuals.

C;T

This is the genotype of User:Watson

Source and license

Adapted from rs997509 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.