i4000319
A SNP in the CFTR gene on chromosome 7. Its most notable genotype is D;I: Carrier of a cystic fibrosis allele - perhaps
- Gene
- CFTR
- Location
- Chr 7117,232,273 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- 23andMe
Genotypes
As shown in 23andMe and AncestryDNA files.
- D;IMost notableBadCarrier of a cystic fibrosis allele - perhaps
- I;IGoodNo summary available.
On SNPedia: (D;I), (I;I). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other CFTR SNPs
- i4000292D;Dcystic fibrosisVery important
- rs74551128A;ACystic fibrosisVery important
- rs113993960-;-Cystic Fibrosis; homozygote for delta F-508 mutationVery important
- rs199826652-;-Cystic Fibrosis; homozygote for delta F-508 mutationVery important
- i4000309A;ACystic FibrosisVery important
- i4000294A;ACystic FibrosisVery important
- i4000296T;TCystic FibrosisVery important
- i4000297A;ACystic FibrosisVery important
Notes
From SNPedia
Notes
previously considered predictive of Cystic Fibrosis, 23andMe has removed it from their reports as unreliable.
D;I
see warning that this genotype may be unreliably called by 23andMe
Source and license
Adapted from i4000319 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.