i6051899
A SNP in the BRCA1 gene. Its most notable genotype is A;C: likely to be BRCA1 variant pathogenic for breast cancer
- Gene
- BRCA1
- Highest magnitude
- 6.0Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;CMost notableBadlikely to be BRCA1 variant pathogenic for breast cancer
- C;CGoodnormal
On SNPedia: (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other BRCA1 SNPs
- rs28897696T;Tcarrier of two copies of BRCA1 variant; likely to be at high risk for breast/ovarian cancerVery important
- rs41286296A;CBRCA1 pathogenic mutation associated with breast cancerVery important
- rs62625306A;CBRCA1 pathogenic mutation associated with breast cancerVery important
- rs62625307A;GBRCA1 pathogenic mutation associated with breast cancerVery important
- rs1800747C;TBRCA1 pathogenic mutation associated with breast cancerVery important
- rs28897672A;Tconsidered a pathogenic BRCA1 breast cancer variantVery important
- rs28897686A;CBRCA1 pathogenic mutation associated with breast cancerVery important
- rs28897698A;CBRCA1 variant considered pathogenic for breast cancerVery important
Notes
From SNPedia
Notes
For information about causal/pathogenic BRCA1 mutations and what they imply about the odds of developing breast cancer, please see the BRCA1 page and links from that page.
A;C
Although this SNP appears to be rs80358158, a mutation pathogenic for breast cancer, due to secrecy policies at 23andMe it is not confirmed.
Source and license
Adapted from i6051899 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.