rs10033464(T;T)

1.4x increased risk of Atrial Fibrillation and cardioembolic stroke

Magnitude
3.0Important
Repute
Bad
Frequency
3%Average of 11 populations
On SNPedia
rs10033464(T;T)
Gene
None listed

Frequency

Share of people with T;T in each HapMap population.

  • Japanese (Tokyo)7%
  • Yoruba (Nigeria)6%
  • Han Chinese (Beijing)5%
  • Luhya (Kenya)5%
  • Chinese (Denver)4%
  • African ancestry (Southwest US)4%
  • Mexican ancestry (Los Angeles)4%
  • Gujarati Indian2%
  • European ancestry (Utah)2%
  • Maasai (Kenya)<1%
  • Tuscan0%

Other genotypes of rs10033464

  1. G;GGood0.92x decreased risk of Atrial Fibrillation and cardioembolic stroke.Minor · 1.969% of people
  2. G;TMost notableBad1.28x increased risk of Atrial Fibrillation and cardioembolic stroke.Important · 3.028% of people

All about rs10033464

Notes

From SNPedia

Two copies of the mutant version which makes affects the formation of the heart and makes people more likely to get Atrial Fibrillation (quivering of the top chambers of the heart caused by chaotic electrical signals) and more likely to have a cardioembolic stroke (blocked blood flow to the brain). But also check the other SNP nearby (rs2200733) which affects Atrial Fibrillation even more. 23andMe gave this a 4 star confidence rating as it has been heavily studied. It has been confirmed in Europeans.

Source and license

Adapted from rs10033464(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.