rs104886456
A SNP in the FANCC gene on chromosome 9. Its most notable genotype is A;A: Fanconi Anemia (FANCC-related)
- Gene
- FANCC
- Location
- Chr 995,172,033 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodcommon in complete genomics
- A;TBadFanconi anemia carrier
- A;AMost notableBadFanconi Anemia (FANCC-related)
SNPedia records rs104886456 on the minus strand: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other FANCC SNPs
- i4000336A;AFanconi Anemia (FANCC-related)Very important
- i4000412A;AFanconi Anemia (FANCC-related)Very important
- i4000413D;DFanconi anemiaVery important
- rs104886459-;-Fanconi anemiaVery important
- rs121917783A;GCarrier of a Fanconi anemia group C mutationImportant
- rs121917784A;GCarrier of a Fanconi anemia group C mutationImportant
Notes
From SNPedia
Notes
rs104886456, also known as IVS4+4A>T, is a SNP in the Fanconi anemia, complementation group C FANCC gene. 23andMe reports that this mutation is carried by approximately 1% of Ashkenazi Jews and is responsible for more than 99% of FANCC-related Fanconi anemia in this population. This same mutation is the most common cause of FANCC-related Fanconi anemia in Japan. The term 23andMe uses for this SNP is i4000336.
Source and license
Adapted from rs104886456 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.