rs121917783
A SNP in the FANCC gene on chromosome 9. Its most notable genotype is A;G: Carrier of a Fanconi anemia group C mutation
- Gene
- FANCC
- Location
- Chr 995,150,056 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- G;GGoodcommon in clinvar
- A;GMost notableBadCarrier of a Fanconi anemia group C mutation
SNPedia records rs121917783 on the minus strand: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other FANCC SNPs
- i4000336A;AFanconi Anemia (FANCC-related)Very important
- i4000412A;AFanconi Anemia (FANCC-related)Very important
- i4000413D;DFanconi anemiaVery important
- rs104886456A;AFanconi Anemia (FANCC-related)Very important
- rs104886459-;-Fanconi anemiaVery important
- rs121917784A;GCarrier of a Fanconi anemia group C mutationImportant
Notes
From SNPedia
Notes
aka c.553C>T (p.Arg185Ter or R185X)
A;G
Unaffected in absence of a second FANCC gene mutation
Source and license
Adapted from rs121917783 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.