rs104886458

A SNP in the C9orf3 gene on chromosome 9. Its most notable genotype is G;G: Fanconi anemia

Gene
C9orf3
Location
Chr 995,101,723 (GRCh38)
Highest magnitude
5.0Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableBadFanconi anemiaVery important · 5.0
  2. A;GBadCarrier of a Fanconi anemia mutationImportant · 3.0
  3. A;AGoodcommon in clinvarTypical · 0.0

SNPedia records rs104886458 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other C9orf3 SNPs

All C9orf3 SNPs

Notes

From SNPedia

Notes

aka c.1661T>C (p.Leu554Pro or L554P)

Source and license

Adapted from rs104886458 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.