rs1050828(T;T)

G6PD deficiency; Hb1Ac value may need adjusting for diabetes diagnosis

Magnitude
4.0Very important
Repute
Bad
Frequency
3%Average of 8 populations
On SNPedia
rs1050828(A;A)Minus strand
Gene
G6PD

Frequency

Share of people with T;T in each HapMap population.

  • Yoruba (Nigeria)14%
  • Luhya (Kenya)8%
  • African ancestry (Southwest US)4%
  • Maasai (Kenya)<1%
  • European ancestry (Utah)0%
  • Han Chinese (Beijing)0%
  • Japanese (Tokyo)0%
  • Mexican ancestry (Los Angeles)0%

Other genotypes of rs1050828

  1. -;CGoodNo summary available.Typical · 0.00% of people
  2. C;TBadG6PD deficiency carrier; Hb1Ac value may need adjusting for diabetes diagnosisImportant · 3.07% of people
  3. -;CGoodNo summary available.Typical · 0.00% of people
  4. C;CGoodcommon in clinvarTypical · 0.090% of people

All about rs1050828

Notes

From SNPedia

The A allele is associated with a reduction in glucose-6-phosphate dehydrogenase (G6PD) and is a diagnostic SNP of the type A- G6PD deficiency genotype. Type A- is predominantly found in individuals with African ancestry. The rs1050828 A allele is also associated with malarial resistance. Because rs1050828 is located on the X chromosome, males are either hemizygous for the normal G allele or this deficiency allele.

Source and license

Adapted from rs1050828(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.