rs10509681(T;T)

No increased risk of GI bleeding on NSAID drugs

Magnitude
1.0Minor
Repute
Good
Frequency
90%Average of 9 populations
On SNPedia
rs10509681(T;T)
Gene
CYP2C8

Frequency

Share of people with T;T in each HapMap population.

  • Han Chinese (Beijing)100%
  • Japanese (Tokyo)100%
  • Yoruba (Nigeria)100%
  • Maasai (Kenya)95%
  • Gujarati Indian92%
  • African ancestry (Southwest US)91%
  • Mexican ancestry (Los Angeles)81%
  • Tuscan78%
  • European ancestry (Utah)75%

Other genotypes of rs10509681

  1. C;CMost notableBad>1.81x risk of GI bleeding with some NSAID drugsWorth knowing · 2.0<1% of people
  2. C;TBadIncreased risk of GI bleeding with NSAIDsMinor · 1.59% of people

All about rs10509681

Source and license

Adapted from rs10509681(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.