rs1051730(A;A)

1.8x increased risk of lung cancer; reduced response to alcohol, therefore possibly increased risk of alcohol abuse

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
4%Average of 11 populations
On SNPedia
rs1051730(T;T)Minus strand
Gene
CHRNA3

Frequency

Share of people with A;A in each HapMap population.

  • Tuscan19%
  • European ancestry (Utah)16%
  • Gujarati Indian6%
  • Mexican ancestry (Los Angeles)5%
  • Yoruba (Nigeria)<1%
  • Maasai (Kenya)<1%
  • Han Chinese (Beijing)0%
  • Japanese (Tokyo)0%
  • African ancestry (Southwest US)0%
  • Chinese (Denver)0%
  • Luhya (Kenya)0%

Other genotypes of rs1051730

  1. G;GGoodSmokes normal (lower) number of cigarettes if a smoker.Worth knowing · 2.073% of people
  2. A;GBad1.3x increased risk of lung cancerWorth knowing · 2.023% of people

All about rs1051730

Source and license

Adapted from rs1051730(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.