rs1051730(G;G)

Smokes normal (lower) number of cigarettes if a smoker.

Magnitude
2.0Worth knowing
Repute
Good
Frequency
73%Average of 11 populations
On SNPedia
rs1051730(C;C)Minus strand
Gene
CHRNA3

Frequency

Share of people with G;G in each HapMap population.

  • Japanese (Tokyo)96%
  • Han Chinese (Beijing)95%
  • Chinese (Denver)93%
  • Luhya (Kenya)91%
  • Yoruba (Nigeria)80%
  • Maasai (Kenya)78%
  • African ancestry (Southwest US)68%
  • Gujarati Indian63%
  • Mexican ancestry (Los Angeles)62%
  • European ancestry (Utah)39%
  • Tuscan36%

Other genotypes of rs1051730

  1. A;GBad1.3x increased risk of lung cancerWorth knowing · 2.023% of people
  2. A;AMost notableBad1.8x increased risk of lung cancer; reduced response to alcohol, therefore possibly increased risk of alcohol abuseWorth knowing · 2.54% of people

All about rs1051730

Notes

From SNPedia

Less nicotine dependence. Also smokes each cigarette less deeply. Therefore there is a reduced risk of lung cancer and a reduced (0.8x) risk of Peripheral Artery Disease. This doesn't affect whether people start smoking though.

Source and license

Adapted from rs1051730(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.