rs111033630
A SNP in the SH2D1A gene on chromosome X. Its most notable genotype is T;T: Lymphoproliferative syndrome 1 (predicted)
- Gene
- SH2D1A
- Location
- Chr X124,365,787 (GRCh38)
- Highest magnitude
- 8.8Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- G;GGoodcommon in clinvar
- G;TBadCarrier of an X-linked mutation for lymphoproliferative syndrome 1
- T;TMost notableBadLymphoproliferative syndrome 1 (predicted)
On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other SH2D1A SNPs
- rs111033623T;TLymphoproliferative syndrome 1 (predicted)Very important
- rs111033624C;CLymphoproliferative syndrome 1 (predicted)Very important
- rs111033625A;ALymphoproliferative syndrome 1 (predicted)Very important
- rs111033626T;TLymphoproliferative syndrome 1 (predicted)Very important
- rs111033627T;TLymphoproliferative syndrome 1 (predicted)Very important
- rs111033628T;TLymphoproliferative syndrome 1 (predicted)Very important
- rs111033629T;TLymphoproliferative syndrome 1 (predicted)Very important
- rs587777612C;CLymphoproliferative syndrome 1 (predicted)Very important
Notes
From SNPedia
Notes
aka c.164G>T (p.Arg55Leu) considered pathogenic for X-linked Lymphoproliferative syndrome, type 1 in ClinVar 23andMe name: i5003042
G;T
see links via main rs-page
T;T
X-linked condition; see links via main rs-page
Source and license
Adapted from rs111033630 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.