rs1129844(A;G)

Significant delay in onset of early-onset Alzheimer's; possibly a 2.5 year delay in onset of late-onset Alzheimer's

Magnitude
2.0Worth knowing
Repute
Good
On SNPedia
rs1129844(A;G)
Gene
CCL11

Other genotypes of rs1129844

  1. A;AMost notableGoodUp to 10 year delay in onset of early-onset Alzheimer's (possibly)Worth knowing · 2.5

All about rs1129844

Notes

From SNPedia

One publication reports that the (A;G) genotype of rs1129844 might significantly delay the onset of early-onset Alzheimer's disease caused by a mutation in the PSEN1 gene. A followup study in late-onset Alzheimer patients found a 2.5 year later onset in those with AG versus GG genotype, but it was not statistically significant. This is an initial report and will need further replications. See additional discussion at rs1129844.

Source and license

Adapted from rs1129844(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.