rs113488022
A SNP in the BRAF gene on chromosome 7. Its most notable genotype is T;T: related to skin moles and melanoma
- Gene
- BRAF
- Location
- Chr 7140,753,336 (GRCh38)
- Highest magnitude
- 3.5Important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TMost notableBadrelated to skin moles and melanoma
- A;AGoodnormal
SNPedia records rs113488022 on the minus strand: (A;A), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other BRAF SNPs
- rs121913341A;CRasopathy; Cardio-facio-cutaneous syndromeVery important
- rs121913355C;TRasopathy; Cardio-facio-cutaneous syndromeVery important
- rs180177034C;GRasopathy; Cardio-facio-cutaneous syndromeVery important
- rs180177035C;TRasopathy; Cardio-facio-cutaneous syndromeVery important
- rs180177040C;TRasopathy; Cardio-facio-cutaneous syndromeVery important
- rs397507465G;TRasopathy; Cardio-facio-cutaneous syndromeVery important
- rs397507479C;TRasopathy; Cardio-facio-cutaneous syndromeVery important
- rs397507483A;CRasopathy; Cardio-facio-cutaneous syndromeVery important
Notes
From SNPedia
Notes
Also known as val600-to-glu (V600E) . Discussed at http://blogs.nature.com/freeassociation/2011/08/melanoma_sequencing_identifies_1.html
Source and license
Adapted from rs113488022 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.