rs1142345(T;T)

Common in clinvar

Magnitude
0.0Typical
Repute
Good
Frequency
92%Average of 11 populations
On SNPedia
rs1142345(A;A)Minus strand
Gene
TPMT

Frequency

Share of people with T;T in each HapMap population.

  • Han Chinese (Beijing)99%
  • Tuscan97%
  • Maasai (Kenya)96%
  • Gujarati Indian95%
  • European ancestry (Utah)95%
  • Japanese (Tokyo)95%
  • Chinese (Denver)95%
  • Yoruba (Nigeria)92%
  • Mexican ancestry (Los Angeles)86%
  • African ancestry (Southwest US)84%
  • Luhya (Kenya)79%

Other genotypes of rs1142345

  1. C;TBadTPMT*3C . impaired drug metabolismImportant · 3.08% of people
  2. C;CMost notableBadpossibly incapable of detoxifying certain drugsImportant · 3.5<1% of people

All about rs1142345

Source and license

Adapted from rs1142345(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.