rs11754661

A SNP in the MTHFD1L gene on chromosome 6. Its most notable genotype is G;G: common on affy axiom data

Gene
MTHFD1L
Location
Chr 6150,885,942 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
4%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon on affy axiom dataTypical · 0.094% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageG;G 94%
  • European ancestry (Utah)G;G 87%
  • Han Chinese (Beijing)G;G 92%
  • Japanese (Tokyo)G;G 93%
  • Yoruba (Nigeria)G;G 100%
  • Chinese (Denver)G;G 93%
  • Gujarati IndianG;G 93%
  • Mexican ancestry (Los Angeles)G;G 97%
  • Maasai (Kenya)G;G 99%
  • TuscanG;G 91%

Conditions, medicines and genes

Other MTHFD1L SNPs

All MTHFD1L SNPs

Notes

From SNPedia

Notes

This SNP in the MTHFD1L gene is associated with late-onset Alzheimer's disease, according to an article in PLoS Genetics.

Source and license

Adapted from rs11754661 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.