rs121908140

A SNP in the CLRN1 gene on chromosome 3. Its most notable genotype is A;C: Carrier of an Usher syndrome type IIIA mutation

Gene
CLRN1
Location
Chr 3150,928,107 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA
Minor allele frequency
<1%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;CMost notableBadCarrier of an Usher syndrome type IIIA mutationImportant · 3.0
  2. A;AGoodcommon in clinvarTypical · 0.0

SNPedia records rs121908140 on the minus strand: (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other CLRN1 SNPs

All CLRN1 SNPs

Notes

From SNPedia

Notes

aka c.567T>G (p.Tyr189Ter or Y189X)

A;C

Unaffected in absence of a second CLRN1 gene mutation

Source and license

Adapted from rs121908140 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.