rs121908767
A SNP in the CFTR gene on chromosome 7. Its most notable genotype is -;ATAGTG: Cystic Fibrosis carrier
- Gene
- CFTR
- Location
- Chr 7117,610,597 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;ATAGTGMost notableBadCystic Fibrosis carrier
- AGTGAT;AGTGATGoodcommon in clinvar
- ATAGTG;ATAGTGGoodcommon in clinvar
- GATAGTG;GATAGTGGoodcommon in clinvar
On SNPedia: (-;ATAGTG), (AGTGAT;AGTGAT), (ATAGTG;ATAGTG), (GATAGTG;GATAGTG). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other CFTR SNPs
- i4000292D;Dcystic fibrosisVery important
- rs74551128A;ACystic fibrosisVery important
- rs113993960-;-Cystic Fibrosis; homozygote for delta F-508 mutationVery important
- rs199826652-;-Cystic Fibrosis; homozygote for delta F-508 mutationVery important
- i4000309A;ACystic FibrosisVery important
- i4000294A;ACystic FibrosisVery important
- i4000296T;TCystic FibrosisVery important
- i4000297A;ACystic FibrosisVery important
Notes
From SNPedia
Notes
Known as 3199del6 or NM_000492.3:c.3067_3072delATAGTG, rs121908767 is considered a (rare) pathogenic mutation for cystic fibrosis. Equivalent to rs397508492 FTDNA & MyHeritage name: VG07S50448
Source and license
Adapted from rs121908767 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.