rs121917737

A SNP in the SFTPA2 gene on chromosome 10. Its most notable genotype is A;C: Idiopathic Pulmonary Fibrosis (IPF) mutation

Gene
SFTPA2
Location
Chr 1079,557,264 (GRCh38)
Highest magnitude
5.5Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CGoodcommon in clinvarTypical · 0.0
  2. A;CMost notableBadIdiopathic Pulmonary Fibrosis (IPF) mutationVery important · 5.5

SNPedia records rs121917737 on the minus strand: (G;G), (G;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other SFTPA2 SNPs

All SFTPA2 SNPs

Notes

From SNPedia

Notes

aka c.692G>T (p.Gly231Val or G231V) see also OMIM 178642.0001

A;C

see links via main rs-page

Source and license

Adapted from rs121917737 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.