rs121917738

A SNP in the SFTPA2 gene on chromosome 10. Its most notable genotype is A;G: Idiopathic Pulmonary Fibrosis (IPF) mutation

Gene
SFTPA2
Location
Chr 1079,557,363 (GRCh38)
Highest magnitude
5.5Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;GMost notableBadIdiopathic Pulmonary Fibrosis (IPF) mutationVery important · 5.5
  2. A;AGoodcommon in clinvarTypical · 0.0

SNPedia records rs121917738 on the minus strand: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other SFTPA2 SNPs

All SFTPA2 SNPs

Notes

From SNPedia

Notes

aka c.593T>C (p.Phe198Ser or F198S) see also OMIM 178642.0002

A;G

see links via main rs-page

Source and license

Adapted from rs121917738 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.