rs121918076

A SNP in the TTR gene on chromosome 18. Its most notable genotype is A;T: TTR-related amyloidosis

Gene
TTR
Location
Chr 1831,595,129 (GRCh38)
Highest magnitude
5.5Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;TMost notableBadTTR-related amyloidosisVery important · 5.5
  2. G;TBadTTR-related amyloidosisVery important · 5.5
  3. T;TGoodcommon in clinvarTypical · 0.0

On SNPedia: (A;T), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other TTR SNPs

All TTR SNPs

Source and license

Adapted from rs121918076 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.