rs121918447

A SNP in the ITGB3 gene on chromosome 17. Its most notable genotype is C;C: Likely miscall if from Ancestry data; otherwise, Glanzmann's thrombasthenia mutation(s)

Gene
ITGB3
Location
Chr 1747,310,169 (GRCh38)
Highest magnitude
3.0Important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBadLikely miscall if from Ancestry data; otherwise, Glanzmann's thrombasthenia mutation(s)Important · 3.0
  2. T;TGoodcommon in clinvarTypical · 0.0

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other ITGB3 SNPs

All ITGB3 SNPs

Notes

From SNPedia

Notes

C;C

Seen too often in Ancestry v2 data compared to reported frequency worldwide, so likely to be a miscall in data from Ancestry. If your data is not from Ancestry, let us know.

Source and license

Adapted from rs121918447 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.