rs1220533001
A SNP in the FGF23 gene on chromosome 12. Its most notable genotype is C;G: Carrier of a tumoral calcinosis mutation
- Gene
- FGF23
- Location
- Chr 124,370,732 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon/normal
- C;GMost notableBadCarrier of a tumoral calcinosis mutation
On SNPedia: (C;C), (C;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other FGF23 SNPs
- rs28937882A;GAutosomal dominant hypophosphatemic rickets (predicted)Very important
- rs104894347C;TAutosomal dominant hypophosphatemic rickets (predicted)Very important
- rs193922701C;GAutosomal dominant hypophosphatemic rickets (predicted)Very important
- rs193922702C;TAutosomal dominant hypophosphatemic rickets (predicted)Very important
- rs104894342C;TCarrier of a tumoral calcinosis mutationImportant
- rs104894343A;GCarrier of a tumoral calcinosis mutationImportant
- rs104894344A;GCarrier of a tumoral calcinosis mutationImportant
- rs863224872C;TCarrier of a tumoral calcinosis mutationImportant
Notes
From SNPedia
Notes
aka c.367G>T (p.Gly123Trp or G123W)
C;G
Unaffected in absence of a second FGF23 gene mutation; see text via main rs-page.
Source and license
Adapted from rs1220533001 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.