rs12255372(G;T)

1.3x increased type-2 diabetes risk

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
27%Average of 11 populations
On SNPedia
rs12255372(G;T)
Gene
TCF7L2

Frequency

Share of people with G;T in each HapMap population.

  • African ancestry (Southwest US)44%
  • Yoruba (Nigeria)43%
  • Tuscan40%
  • Gujarati Indian40%
  • Mexican ancestry (Los Angeles)38%
  • Luhya (Kenya)36%
  • European ancestry (Utah)30%
  • Maasai (Kenya)20%
  • Japanese (Tokyo)4%
  • Chinese (Denver)2%
  • Han Chinese (Beijing)0%

Other genotypes of rs12255372

  1. G;GGoodnormalTypical · 0.068% of people
  2. T;TMost notableBadslight increases (~1.5x) in risk for type-2 diabetes and possibly breast cancer and aggressive prostate cancerWorth knowing · 2.25% of people

All about rs12255372

Notes

From SNPedia

see discussion at rs12255372

Source and license

Adapted from rs12255372(G;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.