rs12255372(T;T)

Slight increases (~1.5x) in risk for type-2 diabetes and possibly breast cancer and aggressive prostate cancer

Magnitude
2.2Worth knowing
Repute
Bad
Frequency
5%Average of 11 populations
On SNPedia
rs12255372(T;T)
Gene
TCF7L2

Frequency

Share of people with T;T in each HapMap population.

  • Tuscan12%
  • European ancestry (Utah)10%
  • Yoruba (Nigeria)9%
  • African ancestry (Southwest US)7%
  • Luhya (Kenya)6%
  • Gujarati Indian4%
  • Mexican ancestry (Los Angeles)3%
  • Maasai (Kenya)1%
  • Japanese (Tokyo)<1%
  • Han Chinese (Beijing)0%
  • Chinese (Denver)0%

Other genotypes of rs12255372

  1. G;GGoodnormalTypical · 0.068% of people
  2. G;TBad1.3x increased type-2 diabetes riskWorth knowing · 2.027% of people

All about rs12255372

Notes

From SNPedia

see discussion at rs12255372

Source and license

Adapted from rs12255372(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.