rs12594375
A SNP in the LIPC gene on chromosome 15. Its most notable genotype is G;G: common in complete genomics
- Gene
- LIPC
- Location
- Chr 1558,440,269 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 14%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 72%
- European ancestry (Utah)G;G 96%
- Han Chinese (Beijing)G;G 50%
- Japanese (Tokyo)G;G 45%
- Yoruba (Nigeria)G;G 74%
- African ancestry (Southwest US)G;G 81%
- Chinese (Denver)G;G 56%
- Gujarati IndianG;G 84%
- Luhya (Kenya)G;G 86%
- Mexican ancestry (Los Angeles)G;G 48%
- Maasai (Kenya)G;G 72%
- TuscanG;G 97%
Related
Other LIPC SNPs
- rs261332A;Aassociated with higher HDL cholesterolWorth knowing
- rs3825776C;C>1.3x increased risk for ALSWorth knowing
- rs6083A;Acommon in clinvarTypical
- rs261334C;Ccommon in complete genomicsTypical
- rs261342C;Ccommon in complete genomicsTypical
- rs2070895G;Gcommon in complete genomicsTypical
- rs3829462C;Ccommon in clinvarTypical
- rs8023503C;Ccommon in complete genomicsTypical
Source and license
Adapted from rs12594375 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.