rs12623467
A SNP in the NRXN1 gene on chromosome 2. Its most notable genotype is C;C: common in complete genomics
- Gene
- NRXN1
- Location
- Chr 250,997,951 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 21%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 3 HapMap populations.
- AverageC;C 58%
- European ancestry (Utah)C;C 91%
- Han Chinese (Beijing)C;C 40%
- Japanese (Tokyo)C;C 42%
Related
Notes
From SNPedia
Notes
rs12623467 increases susceptibility to Substance dependence, Nicotine 2.09 times for carriers of the C allele
Source and license
Adapted from rs12623467 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.