rs12720441

A SNP in the KCNH2 gene on chromosome 7. Its most notable genotype is A;G: Romano-Ward Long QT Syndrome

Gene
KCNH2
Location
Chr 7150,950,216 (GRCh38)
Highest magnitude
5.0Very important
Tested on
AncestryDNA
Minor allele frequency
<1%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in complete genomicsTypical · 0.0100% of people
  2. A;GMost notableBadRomano-Ward Long QT SyndromeVery important · 5.00% of people

SNPedia records rs12720441 on the minus strand: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageG;G 100% A;G 0%
  • European ancestry (Utah)G;G 100% A;G 0%
  • Han Chinese (Beijing)G;G 100% A;G 0%
  • Japanese (Tokyo)G;G 100% A;G 0%
  • Yoruba (Nigeria)G;G 100% A;G 0%

Other KCNH2 SNPs

All KCNH2 SNPs

Source and license

Adapted from rs12720441 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.