rs12777823(A;G)

Avoid Plavix, higher risk for adverse cardiovascular events.

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
34%Average of 11 populations
On SNPedia
rs12777823(A;G)
Gene
LOC100130970

Frequency

Share of people with A;G in each HapMap population.

  • Han Chinese (Beijing)49%
  • Japanese (Tokyo)44%
  • Yoruba (Nigeria)41%
  • Luhya (Kenya)40%
  • Maasai (Kenya)35%
  • Chinese (Denver)35%
  • Gujarati Indian33%
  • African ancestry (Southwest US)32%
  • European ancestry (Utah)25%
  • Mexican ancestry (Los Angeles)24%
  • Tuscan19%

Other genotypes of rs12777823

  1. A;AMost notableBadAvoid Plavix, higher risk for adverse cardiovascular events. CYP2C19 poor metabolizer.Important · 3.56% of people
  2. G;GGoodcommon in clinvarTypical · 0.059% of people

All about rs12777823

Notes

From SNPedia

Neighboring rs4244285 is a more reliable predictor, but this genotype is linked to being a poor metabolizer of several popular medicines; patients prescribed Plavix (Clopidogrel) have higher risk for adverse cardiovascular events.

Source and license

Adapted from rs12777823(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.