rs137854567
A SNP in the APC gene on chromosome 5. Its most notable genotype is C;T: Familial adenomatous polyposis or benign? Unclear.
- Gene
- APC
- Location
- Chr 5112,819,272 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- AncestryDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- C;TMost notableNot ratedFamilial adenomatous polyposis or benign? Unclear.
On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other APC SNPs
- rs2229992G;TFamilial Adenomatous PolyposisVery important
- rs62619935C;TFamilial Adenomatous PolyposisVery important
- rs121913331C;TFamilial Adenomatous PolyposisVery important
- rs121913333C;TFamilial Adenomatous PolyposisVery important
- rs137854568C;TFamilial Adenomatous PolyposisVery important
- rs137854569C;GFamilial Adenomatous PolyposisVery important
- rs137854572C;TFamilial Adenomatous PolyposisVery important
- rs137854575A;CFamilial Adenomatous PolyposisVery important
Notes
From SNPedia
Notes
C;T
Originally reported as associated with familial adenomatous polyposis, but currently listed as either benign or of unknown significance in ClinVar.
Source and license
Adapted from rs137854567 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.