rs142129409

A SNP in the PADI3 gene on chromosome 1. Its most notable genotype is A;A: Uncombable hair syndrome

Gene
PADI3
Location
Chr 117,262,194 (GRCh38)
Highest magnitude
3.3Important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadUncombable hair syndromeImportant · 3.3
  2. A;TBadCarrier of an uncombable hair syndrome variantImportant · 3.0
  3. T;TGoodcommon/normalTypical · 0.0

On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other PADI3 SNPs

All PADI3 SNPs

Notes

From SNPedia

Notes

Uncombable hair syndrome variant in PADI3 gene, c.335T>A or p.Leu112His

A;A

see uncombable hair syndrome

A;T

see uncombable hair syndrome; unaffected unless carrying another related mutation

Source and license

Adapted from rs142129409 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.