rs144080386

A SNP in the PADI3 gene on chromosome 1. Its most notable genotype is T;T: Uncombable hair syndrome

Gene
PADI3
Location
Chr 117,270,928 (GRCh38)
Highest magnitude
3.3Important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon/normalTypical · 0.0
  2. C;TBadCarrier of an uncombable hair syndrome variantImportant · 3.0
  3. T;TMost notableBadUncombable hair syndromeImportant · 3.3

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other PADI3 SNPs

All PADI3 SNPs

Notes

From SNPedia

Notes

Uncombable hair syndrome variant in PADI3 gene, c.881C>T or p.Ala294Val

C;T

see uncombable hair syndrome; unaffected unless carrying another related mutation

T;T

see uncombable hair syndrome

Source and license

Adapted from rs144080386 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.