rs146597587

A SNP in the IL33 gene on chromosome 9. Its most notable genotype is C;G: Reduced odds of developing asthma

Gene
IL33
Location
Chr 96,255,967 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;GMost notableGoodReduced odds of developing asthmaWorth knowing · 2.0
  2. G;GGoodcommon/normalTypical · 0.0

On SNPedia: (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other IL33 SNPs

All IL33 SNPs

Notes

From SNPedia

Notes

rs146597587, also known as c.487-1G>C, represents a variant in the IL33 gene located on chromosome 9. Based on a study of UK BioBank participants, carriers of a rs146597587(C) allele have 43% lower odds of developing asthma (OR 0.57, CI:0.51-0.65, p=9.6x10e−19).

C;G

see text and links via main rs-page

Source and license

Adapted from rs146597587 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.