rs1532268
A SNP in the MTRR gene on chromosome 5. Its most notable genotype is T;T: increased risk
- Gene
- MTRR
- Location
- Chr 57,878,066 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 25%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1532268 on the minus strand: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 8% C;C 55%
- European ancestry (Utah)T;T 8% C;C 46%
- Han Chinese (Beijing)T;T 2% C;C 75%
- Japanese (Tokyo)T;T <1% C;C 90%
- Yoruba (Nigeria)T;T 3% C;C 59%
- African ancestry (Southwest US)T;T 9% C;C 43%
- Chinese (Denver)T;T 3% C;C 72%
- Gujarati IndianT;T 15% C;C 42%
- Luhya (Kenya)T;T 13% C;C 46%
- Mexican ancestry (Los Angeles)T;T 2% C;C 70%
- Maasai (Kenya)T;T 22% C;C 24%
- TuscanT;T 12% C;C 38%
Related
Other MTRR SNPs
- rs1801394G;G1.4x higher risk for meningiomasWorth knowing
- rs9332G;Gcommon in complete genomicsTypical
- rs10380C;Ccommon in complete genomicsTypical
- rs162036A;Acommon in complete genomicsTypical
- rs1802059G;Gcommon in clinvarTypical
- rs2287780C;Ccommon in clinvarTypical
- rs2303080T;Tcommon in clinvarTypical
- rs3776463A;Acommon genotypeTypical
Notes
From SNPedia
Notes
T;T
of ventricular septal defect
Source and license
Adapted from rs1532268 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.