rs17594526
A SNP in the TCF4 gene on chromosome 18. Its most notable genotype is C;C: common in complete genomics
- Gene
- TCF4
- Location
- Chr 1855,391,007 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 6%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageC;C 81%
- European ancestry (Utah)C;C 95%
- Han Chinese (Beijing)C;C 100%
- Japanese (Tokyo)C;C 100%
- Yoruba (Nigeria)C;C 63%
- African ancestry (Southwest US)C;C 83%
- Luhya (Kenya)C;C 59%
- Mexican ancestry (Los Angeles)C;C 95%
- Maasai (Kenya)C;C 46%
- TuscanC;C 94%
Related
Other TCF4 SNPs
- rs613872G;G~20-30x higher risk for Fuchs' dystrophy, a corneal disorderWorth knowing
- rs17595731C;C~20-30x higher risk for Fuchs' dystrophy, a corneal disorderWorth knowing
- rs9960767C;C1.4x increased risk for schizophreniaMinor
- rs10401120C;Ccommon in complete genomicsTypical
- rs17512836T;Tcommon in complete genomicsTypical
- rs17597926G;Gcommon in complete genomicsTypical
Source and license
Adapted from rs17594526 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.