rs17879685
A SNP in the CYP2C19 gene on chromosome 10. Its most notable genotype is C;C: normal
- Gene
- CYP2C19
- Location
- Chr 1094,849,995 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CMost notableGoodnormal
- C;TNot ratedcarrier of one CYP2C19*13 allele
- T;TNot ratedCYP2C19*13 homozygote
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 8 HapMap populations.
- AverageC;C 97% C;T 3% T;T 0%
- Han Chinese (Beijing)C;C 99% C;T 2% T;T 0%
- Yoruba (Nigeria)C;C 94% C;T 6% T;T 0%
- African ancestry (Southwest US)C;C 97% C;T 4% T;T 0%
- Gujarati IndianC;C 99% C;T 1% T;T 0%
- Luhya (Kenya)C;C 92% C;T 8% T;T 0%
- Mexican ancestry (Los Angeles)C;C 98% C;T 2% T;T 0%
- Maasai (Kenya)C;C 97% C;T 3% T;T 0%
- TuscanC;C 99% C;T 1% T;T 0%
Related
Other CYP2C19 SNPs
- rs4244285A;Apoor metabolizer of several popular medicines; patients prescribed Plavix get less benefit, and have higher risk for adverse cardiovascular eventsVery important
- rs6413438T;TCYP2C19*10 homozygoteImportant
- rs41291556C;CCYP2C19*8 homozygoteImportant
- rs56337013T;TCYP2C19*5 homozygoteImportant
- rs28399504G;Gpoor metabolizerWorth knowing
- rs4986893A;Apoor metabolizer of several commonly prescribed drugsWorth knowing
- rs12248560C;TCYP2C19*17 ultra fast metabolizer; drug metabolism effects; also 0.77x decreased breast cancer riskWorth knowing
- rs3758580C;Ccommon/normalTypical
Genosets
- Gs152CYP2C19 Poor MetabolizerImportant
- Gs151CYP2C19 Intermediate MetabolizerImportant
- Gs150CYP2C19 normal/rapid metabolizer (most likely)Minor
Genosets combine several genotypes. Twofold checks them in your report.
Notes
From SNPedia
Notes
The rs17879685(T) SNP defines the CYP2C19 allele known as CYP2C19*13.
Source and license
Adapted from rs17879685 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.