rs1800098
A SNP in the CFTR gene on chromosome 7. Its most notable genotype is C;G: unaffected carrier of an allele associated with vas deferens condition?
- Gene
- CFTR
- Location
- Chr 7117,590,400 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;GMost notableBadunaffected carrier of an allele associated with vas deferens condition?
- G;GGoodcommon in clinvar
On SNPedia: (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other CFTR SNPs
- i4000292D;Dcystic fibrosisVery important
- rs74551128A;ACystic fibrosisVery important
- rs113993960-;-Cystic Fibrosis; homozygote for delta F-508 mutationVery important
- rs199826652-;-Cystic Fibrosis; homozygote for delta F-508 mutationVery important
- i4000309A;ACystic FibrosisVery important
- i4000294A;ACystic FibrosisVery important
- i4000296T;TCystic FibrosisVery important
- i4000297A;ACystic FibrosisVery important
Notes
From SNPedia
Notes
C;G
Prior to 2012, this genotype represented a carrier of a cystic fibrosis allele, but since 2012, the CFTR2 database annotates this as "non CF causing". It is associated in OMIM, when present in someone also carrying a bona fide CF mutation, as associated with a vas deferens condition.
Source and license
Adapted from rs1800098 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.