rs1800469(A;A)

Higher TGF-β1 levels

Magnitude
1.0Minor
Repute
Not rated
Frequency
15%Average of 11 populations
On SNPedia
rs1800469(T;T)Minus strand
Gene
TGFB1

Frequency

Share of people with A;A in each HapMap population.

  • Chinese (Denver)39%
  • Han Chinese (Beijing)24%
  • Japanese (Tokyo)20%
  • Tuscan18%
  • Gujarati Indian17%
  • Mexican ancestry (Los Angeles)12%
  • European ancestry (Utah)11%
  • Yoruba (Nigeria)9%
  • Luhya (Kenya)6%
  • African ancestry (Southwest US)5%
  • Maasai (Kenya)4%

Other genotypes of rs1800469

  1. G;GMost notableNot ratedlower TGF-β1 levels, higher risk for COPD?Minor · 1.045% of people
  2. A;GNot ratedslightly higher TGF-β1 levels, higher risk for COPD?Minor · 1.040% of people

All about rs1800469

Notes

From SNPedia

Higher TGF-β1 levels by preventing AP1 from downregulating TGF-β1 production.

Source and license

Adapted from rs1800469(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.