rs1800566(A;G)

Possible Lower Lung Cancer risk

Magnitude
1.8Minor
Repute
Good
Frequency
39%Average of 11 populations
On SNPedia
rs1800566(C;T)Minus strand
Gene
NQO1

Frequency

Share of people with A;G in each HapMap population.

  • Han Chinese (Beijing)55%
  • Japanese (Tokyo)51%
  • Chinese (Denver)50%
  • Gujarati Indian42%
  • Mexican ancestry (Los Angeles)40%
  • Tuscan35%
  • Luhya (Kenya)35%
  • European ancestry (Utah)32%
  • African ancestry (Southwest US)32%
  • Yoruba (Nigeria)28%
  • Maasai (Kenya)26%

Other genotypes of rs1800566

  1. G;GGoodcommon in clinvarTypical · 0.052% of people
  2. A;AMost notableBadBenzene toxicity; cancer risksImportant · 3.110% of people

All about rs1800566

Notes

From SNPedia

rs1800566 may decrease susceptibility to Lung Cancer 0.48 times for heterozygotes (CT) due to the presence of the T allele reducing the rate at which the pro-carcinogenic activating NOD1 enzyme operates PMID 15498787

References

Source and license

Adapted from rs1800566(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.