rs1800730
A SNP in the LOC108783645 gene on chromosome 6. Its most notable genotype is T;T: affected by a mild form of hemochromatosis
- Gene
- LOC108783645
- Location
- Chr 626,090,957 (GRCh38)
- Highest magnitude
- 2.6Worth knowing
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AGoodcommon in clinvar
- A;TBadcarrier for a mild form of hemochromatosis
- T;TMost notableBadaffected by a mild form of hemochromatosis
On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other LOC108783645 SNPs
- rs1800562A;ATwo copies of C282Y, likely affected by hemochromatosis which may be serious if male or post-menopausal.Very important
- rs1799945G;GTwo copies of H63D, likely affected by mild form of hemochromatosisVery important
- rs28934595A;CCarrier of a hemochromatosis variantImportant
- rs28934596C;TCarrier of a hemochromatosis variantImportant
- rs28934597C;GCarrier of a hemochromatosis variantImportant
- rs111033563A;CCarrier of a hemochromatosis variantImportant
- rs146519482G;TCarrier of a hemochromatosis variantImportant
- rs797045145A;GCarrier of a hemochromatosis variantImportant
Notes
From SNPedia
Notes
rs1800730, also known as S65C or Ser65Cys, is associated with a mild form of hemochromatosis ; in SNPedia, see also i3002468.
Source and license
Adapted from rs1800730 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.