rs1800961
A SNP in the HNF4A gene on chromosome 20. Its most notable genotype is C;C: common in complete genomics
- Gene
- HNF4A
- Location
- Chr 2044,413,724 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 2%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 8 HapMap populations.
- AverageC;C 97%
- European ancestry (Utah)C;C 93%
- Han Chinese (Beijing)C;C 96%
- Japanese (Tokyo)C;C 99%
- Yoruba (Nigeria)C;C 100%
- Chinese (Denver)C;C 95%
- Gujarati IndianC;C 95%
- Mexican ancestry (Los Angeles)C;C 98%
- TuscanC;C 97%
Related
Conditions, medicines and genes
Other HNF4A SNPs
- rs137853334C;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs137853335C;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs137853336C;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs137853337A;Gassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs137853338G;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs587777732C;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs745975C;Ccommon in clinvarTypical
- rs1885088G;GNo summary available.Typical
Notes
From SNPedia
Show notes, about 120 words
per the 23andMe blog, the minor allele of this SNP (T) was associated with decreased HDL cholesterol {| border="1" |- !SNP !Rarer allele !LDL !HDL !TG |- | rs6544713 || T || + || || |- | rs2650000 || A || + || || |- | rs471364 || C || || - || |- | rs1800961 || T || || - || |- | rs7679 || C || || - || + |- | rs2967605 || T || || - || |- | rs2409722 || T || || || - |- | rs10903129 || A || - || - || - |- | rs6756629 || A || - || + || - |- | rs12670798 || C || + || + || + |- | rs7395662 || A || - || + || + |- | rs174570 || T || - || - || + |- | rs2271293 || A || - || + || - |- | rs2624265 || C || || || + |- | rs2167079 || T || || + || |- | rs9891572 || T || || + || |- | rs4844614 || T || + || || |- | rs5031002 || G || + || || |- |}
Source and license
Adapted from rs1800961 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.