rs745975
A SNP in the HNF4A gene on chromosome 20. Its most notable genotype is C;C: common in clinvar
- Gene
- HNF4A
- Location
- Chr 2044,406,053 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- 19%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs745975 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 70%
- European ancestry (Utah)C;C 56%
- Han Chinese (Beijing)C;C 66%
- Japanese (Tokyo)C;C 70%
- Yoruba (Nigeria)C;C 87%
- African ancestry (Southwest US)C;C 63%
- Chinese (Denver)C;C 61%
- Gujarati IndianC;C 69%
- Luhya (Kenya)C;C 82%
- Mexican ancestry (Los Angeles)C;C 79%
- Maasai (Kenya)C;C 74%
- TuscanC;C 61%
Related
Other HNF4A SNPs
- rs137853334C;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs137853335C;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs137853336C;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs137853337A;Gassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs137853338G;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs587777732C;Tassociated with MODY1; maturity onset of diabetes in the young (type 1)Worth knowing
- rs1800961C;Ccommon in complete genomicsTypical
- rs1885088G;GNo summary available.Typical
Source and license
Adapted from rs745975 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.