rs1801131(G;G)

Number of risks. Complex.

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
7%Average of 11 populations
On SNPedia
rs1801131(C;C)Minus strand
Gene
MTHFR

Frequency

Share of people with G;G in each HapMap population.

  • Gujarati Indian16%
  • Tuscan13%
  • European ancestry (Utah)12%
  • Maasai (Kenya)8%
  • Chinese (Denver)7%
  • Mexican ancestry (Los Angeles)5%
  • Luhya (Kenya)5%
  • Han Chinese (Beijing)2%
  • Japanese (Tokyo)2%
  • African ancestry (Southwest US)2%
  • Yoruba (Nigeria)<1%

Other genotypes of rs1801131

  1. T;TGoodmost common genotypeTypical · 0.060% of people
  2. G;TBadPossibly impaired folate metabolismWorth knowing · 2.134% of people

All about rs1801131

Notes

From SNPedia

MTHFR rs1801131 is involved in converting 5-methylfolate (5MTHF) to tetrahydrofolate (THF). Unlike MTHFR C677T, this mutation does not lead to elevated homocysteine levels.

Source and license

Adapted from rs1801131(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.