rs1801155(A;A)

Risk of colon cancer and familial adenomatous polyposis (FAP) which usually progresses to malignancy

Magnitude
6.0Very important
Repute
Bad
On SNPedia
rs1801155(A;A)
Gene
APC

Other genotypes of rs1801155

  1. A;TBadrisk of colon cancer; familial adenomatous polyposisVery important · 4.0
  2. T;TGoodcommon in complete genomicsTypical · 0.0

All about rs1801155

Notes

From SNPedia

See discussion at: Rs1801155; also known as rs28933380; related to colorectal cancer. The APC I1307K mutation is primarily found in people of Ashkenazi Jewish heritage (Jews of Eastern European or Russian ancestry). Researchers believe that 6% of Ashkenazi Jews carry this gene mutation, making them at a significantly higher risk for developing colorectal cancer. It is also found among Sephardi and Mizrahi Jews and Muslim and Christian Palestinian Arabs, as well as Negev Bedouin. Many patients with colorectal cancer experience no symptoms in the early stages. In fact, symptoms may not appear until the disease is in advanced stage. Routine colorectal screening is very important. Even children from 11 years of age should be screened if there is a family history of colorectal cancer. * APC I1307K and Colorectal Cancer - Johns Hopkins Hereditary Colorectal Cancer Website

Source and license

Adapted from rs1801155(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.