rs1805008(C;T)

Red hair carrier, higher risk of melanoma

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
6%Average of 10 populations
On SNPedia
rs1805008(C;T)
Gene
MC1R

Frequency

Share of people with C;T in each HapMap population.

  • European ancestry (Utah)26%
  • African ancestry (Southwest US)9%
  • Tuscan9%
  • Yoruba (Nigeria)4%
  • Mexican ancestry (Los Angeles)3%
  • Gujarati Indian3%
  • Han Chinese (Beijing)2%
  • Chinese (Denver)2%
  • Luhya (Kenya)<1%
  • Maasai (Kenya)<1%

Other genotypes of rs1805008

  1. C;CGoodcommon in clinvarTypical · 0.094% of people
  2. T;TMost notableBad~7-10x higher likelihood of red hair; higher risk of melanomaImportant · 3.00% of people

All about rs1805008

Notes

From SNPedia

this genotype raises the melanoma risk 42% (95% CI, 15–76%) higher than that among persons not carrying a similar allele.

References

Source and license

Adapted from rs1805008(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.