rs2145418(A;C)

5.0x increased thyroid cancer risk

Magnitude
2.2Worth knowing
Repute
Bad
Frequency
38%Average of 11 populations
On SNPedia
rs2145418(G;T)Minus strand
Gene
None listed

Frequency

Share of people with A;C in each HapMap population.

  • Chinese (Denver)50%
  • African ancestry (Southwest US)46%
  • Luhya (Kenya)43%
  • Han Chinese (Beijing)39%
  • Yoruba (Nigeria)39%
  • Maasai (Kenya)39%
  • Japanese (Tokyo)38%
  • Mexican ancestry (Los Angeles)37%
  • Gujarati Indian33%
  • European ancestry (Utah)31%
  • Tuscan28%

Other genotypes of rs2145418

  1. C;CMost notableBad9.2x increased thyroid cancer riskWorth knowing · 2.57% of people
  2. A;AGoodnormalTypical · 0.055% of people

All about rs2145418

Notes

From SNPedia

but only reported in a single study, with no replication in 9 years. Population frequency for the genotype is also ~30%, far too high to be as negative as this sounds.

Source and license

Adapted from rs2145418(G;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.