rs2145418(C;C)

9.2x increased thyroid cancer risk

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
7%Average of 11 populations
On SNPedia
rs2145418(G;G)Minus strand
Gene
None listed

Frequency

Share of people with C;C in each HapMap population.

  • Mexican ancestry (Los Angeles)21%
  • Yoruba (Nigeria)13%
  • Maasai (Kenya)8%
  • African ancestry (Southwest US)7%
  • Han Chinese (Beijing)6%
  • Chinese (Denver)6%
  • Tuscan5%
  • European ancestry (Utah)4%
  • Luhya (Kenya)4%
  • Japanese (Tokyo)3%
  • Gujarati Indian1%

Other genotypes of rs2145418

  1. A;CBad5.0x increased thyroid cancer riskWorth knowing · 2.238% of people
  2. A;AGoodnormalTypical · 0.055% of people

All about rs2145418

Notes

From SNPedia

but only reported in a single study, with no replication in 9 years. Population frequency for the genotype is also ~5%, far too high to be as negative as this sounds.

Source and license

Adapted from rs2145418(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.