rs219778
A SNP in the LOC105369301 gene on chromosome 21. Its most notable genotype is A;A: common in complete genomics
- Gene
- LOC105369301
- Location
- Chr 2136,462,343 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 25%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs219778 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageA;A 66%
- European ancestry (Utah)A;A 57%
- Han Chinese (Beijing)A;A 99%
- Japanese (Tokyo)A;A 98%
- Chinese (Denver)A;A 97%
- Gujarati IndianA;A 76%
- Luhya (Kenya)A;A 27%
- Mexican ancestry (Los Angeles)A;A 61%
- Maasai (Kenya)A;A 23%
- TuscanA;A 55%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
DeCode reports that carriers of two T alleles at rs219778 have a slightly increased risk of developing kidney stones.
Source and license
Adapted from rs219778 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.