rs2200733(T;T)

1.5x increased risk of Atrial Fibrillation and ischemic stroke.

Magnitude
3.0Important
Repute
Bad
Frequency
9%Average of 11 populations
On SNPedia
rs2200733(T;T)
Gene
LOC729065

Frequency

Share of people with T;T in each HapMap population.

  • Chinese (Denver)30%
  • Japanese (Tokyo)24%
  • Han Chinese (Beijing)20%
  • Yoruba (Nigeria)7%
  • Maasai (Kenya)5%
  • Mexican ancestry (Los Angeles)3%
  • Gujarati Indian3%
  • Luhya (Kenya)3%
  • Tuscan2%
  • European ancestry (Utah)2%
  • African ancestry (Southwest US)2%

Other genotypes of rs2200733

  1. C;CGood0.86x decreased risk of Atrial FibrillationMinor · 1.955% of people
  2. C;TMost notableBad1.4x increased risk of Atrial Fibrillation and ischemic stroke.Important · 3.036% of people

All about rs2200733

Notes

From SNPedia

Two defective copies. This affects the formation of the heart and gives a higher risk of Atrial Fibrillation (quivering of the top part of the heart), and Cardioembolic and Ischemic strokes (blocked blood flow to the brain). Based on several quality studies, and confirmed for Europeans and Asians. It's recommended to eat a heart-healthy diet, and only drink alcohol in moderation, to lower the risk.

Source and license

Adapted from rs2200733(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.