rs2230365

A SNP in the LOC100287329 gene on chromosome 6. Its most notable genotype is C;C: common in complete genomics

Gene
LOC100287329
Location
Chr 631,557,671 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
14%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.076% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 76%
  • European ancestry (Utah)C;C 75%
  • Han Chinese (Beijing)C;C 72%
  • Japanese (Tokyo)C;C 54%
  • Yoruba (Nigeria)C;C 95%
  • African ancestry (Southwest US)C;C 91%
  • Chinese (Denver)C;C 58%
  • Gujarati IndianC;C 59%
  • Luhya (Kenya)C;C 92%
  • Mexican ancestry (Los Angeles)C;C 76%
  • Maasai (Kenya)C;C 93%
  • TuscanC;C 73%

Other LOC100287329 SNPs

All LOC100287329 SNPs

Notes

From SNPedia

Notes

Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis. Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB transcription factors and non-Hodgkin lymphoma risk.

Source and license

Adapted from rs2230365 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.